Understanding How Long Modafinil Effects

Modafinil is a wake-promoting drug that increases extracellular dopamine by inhibiting dopamine transporters. It acts on a number of neurochemical systems involved in sleep/wake regulation, including the hypothalamic-pituitary-adrenal axis, norepinephrine, serotonin, orexin, adenosine, histamine-3, and melatonin. In a double-blind placebo controlled study, Modafinil improved alertness and performance in recurrent nearly 30-h episodes of forced desynchrony […]